Hello!
Has anyone had any success with treating the Genital Anesthesia portion of PSSD? It turns out I can have sex, when with a women. And if I use viagra I can perform quite well. It just doesn't feel great. Any experimentations I should be aware of?
Thanks!
Genital Anesthesia Treatments/Orgamsic Dysfunction Treatment
-
- Posts: 31
- Joined: Sun Mar 05, 2023 9:43 am
- Contact:
- Determined-Mind
- Posts: 101
- Joined: Tue Jan 09, 2024 11:11 am
- Contact:
Re: Genital Anesthesia Treatments/Orgamsic Dysfunction Treatment
Hello,
Do you manage to feel a little sexual pleasure? Or do you feel zero/10?
A year and a half ago, I was at 2/10 of pleasure.
I went up to 4/10 with 150 mg of bupropion XL in 3 days! It was super encouraging. This effect lasted several months.
When I upped the dose to 300 mg, I went back down to my base level (2/10).
150 mg bupropion + 20 mg buspirone made me calmer and my sensory experience more qualitative (better sensory attention).
Then I had the idea of switching back to bupropion. And then surprise! A window of 6/10 pleasure with 300 mg bupropion and 20 mg buspirone a day.
Unfortunately, I had insomnia and stopped.
But if I had to do it all over again, I'd try to manage the insomnia with 1g of arginine at bedtime. I've recently noticed that it helps me sleep through medication-induced insomnia. If that's not enough, I'll try increasing the dose and/or combining it with melatonin.
Then I tried flibanserin, but it made me feel worse. My bodily sensations of pleasure diminished and my mood worsened (I became desperate).
When I stopped all the medication, I fell to 0/10 sensations, i.e. below my baseline.
A few months ago, I tried to reintroduce bupropion but had no benefit on sensations. According to what I've read, bupropion acts mainly on noradrenaline. This neurotransmitter can amplify the sensations experienced in an inverted U-shaped curve. Since I'm at zero, it makes sense: 0*X=0
Right now I'm trying to get my pleasure back up. I've started taking NAC. I read on Reddit that one person had lasting improvements with 1500 mg a day. These improvements were maintained even after stopping NAC.
Glutamate deregulation is suspected in anhedonia problems.
Stay tuned!
If you experience improvements in sexual pleasure, let us know!
PS: I am a woman
Do you manage to feel a little sexual pleasure? Or do you feel zero/10?
A year and a half ago, I was at 2/10 of pleasure.
I went up to 4/10 with 150 mg of bupropion XL in 3 days! It was super encouraging. This effect lasted several months.
When I upped the dose to 300 mg, I went back down to my base level (2/10).
150 mg bupropion + 20 mg buspirone made me calmer and my sensory experience more qualitative (better sensory attention).
Then I had the idea of switching back to bupropion. And then surprise! A window of 6/10 pleasure with 300 mg bupropion and 20 mg buspirone a day.
Unfortunately, I had insomnia and stopped.
But if I had to do it all over again, I'd try to manage the insomnia with 1g of arginine at bedtime. I've recently noticed that it helps me sleep through medication-induced insomnia. If that's not enough, I'll try increasing the dose and/or combining it with melatonin.
Then I tried flibanserin, but it made me feel worse. My bodily sensations of pleasure diminished and my mood worsened (I became desperate).
When I stopped all the medication, I fell to 0/10 sensations, i.e. below my baseline.
A few months ago, I tried to reintroduce bupropion but had no benefit on sensations. According to what I've read, bupropion acts mainly on noradrenaline. This neurotransmitter can amplify the sensations experienced in an inverted U-shaped curve. Since I'm at zero, it makes sense: 0*X=0
Right now I'm trying to get my pleasure back up. I've started taking NAC. I read on Reddit that one person had lasting improvements with 1500 mg a day. These improvements were maintained even after stopping NAC.
Glutamate deregulation is suspected in anhedonia problems.
Stay tuned!
If you experience improvements in sexual pleasure, let us know!
PS: I am a woman
You're looking for a cure or want to help the community? I've created an interactive table listing possible treatments for PSSD.
Feel free to contribute anonymously and share your experiences with different substances (+150 options)!
Feel free to contribute anonymously and share your experiences with different substances (+150 options)!
- Determined-Mind
- Posts: 101
- Joined: Tue Jan 09, 2024 11:11 am
- Contact:
Re: Genital Anesthesia Treatments/Orgamsic Dysfunction Treatment
Other people have experienced improvements in pleasure with other substances. I've listed them all in a table : https://coda.io/d/Treatment-options-for ... Onz#_lu6pc
You can filter treatments according to your symptoms (erectile dysfunction, loss of libido, sexual pleasure, orgasm...) using the "Could be good for" button.
You can search for a substance using the Search bar on the top right of the table
Fenugreek - Trigonella foenum-graecum could be interesting for orgasm and pleasure.
You can filter treatments according to your symptoms (erectile dysfunction, loss of libido, sexual pleasure, orgasm...) using the "Could be good for" button.
You can search for a substance using the Search bar on the top right of the table
Fenugreek - Trigonella foenum-graecum could be interesting for orgasm and pleasure.
You're looking for a cure or want to help the community? I've created an interactive table listing possible treatments for PSSD.
Feel free to contribute anonymously and share your experiences with different substances (+150 options)!
Feel free to contribute anonymously and share your experiences with different substances (+150 options)!
Re: Genital Anesthesia Treatments/Orgamsic Dysfunction Treatment
I've read Flibanserine moderately antagonize D4 Receptors, could this be related to your discomfort ?
- Determined-Mind
- Posts: 101
- Joined: Tue Jan 09, 2024 11:11 am
- Contact:
Re: Genital Anesthesia Treatments/Orgamsic Dysfunction Treatment
In my opinion, what was unpleasant for me about flibanserin was its POST-synaptic agonist of 5-HT1A receptors (I felt very hopeless on it - it was chemical despair)
Buspirone, which is a PRE-synaptic 5HT1A agonist, tends to make you feel hopeful
Buspirone, which is a PRE-synaptic 5HT1A agonist, tends to make you feel hopeful
You're looking for a cure or want to help the community? I've created an interactive table listing possible treatments for PSSD.
Feel free to contribute anonymously and share your experiences with different substances (+150 options)!
Feel free to contribute anonymously and share your experiences with different substances (+150 options)!
Re: Genital Anesthesia Treatments/Orgamsic Dysfunction Treatment
That's very interesting I had a similar effect (despair) only with Ashwagandha.Determined-Mind wrote: ↑Sun Feb 04, 2024 7:42 am In my opinion, what was unpleasant for me about flibanserin was its POST-synaptic agonist of 5-HT1A receptors (I felt very hopeless on it - it was chemical despair)
Buspirone, which is a PRE-synaptic 5HT1A agonist, tends to make you feel hopeful
Who is online
Users browsing this forum: Google [Bot] and 0 guests