Clomipramine and delayed ejaculation: neurophysiological tests

This is for hypothesis and even educated speculation.
cosmo
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Clomipramine and delayed ejaculation: neurophysiological tests

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I found this old article on the mechanism by which clomipramine delays ejaculation:

Effectiveness mechanism of chlomipramine by neurophysiological tests in subjects with true premature ejaculation

https://pubmed.ncbi.nlm.nih.gov/1897755/

Summary. “The effectiveness mechanism of the chlomipramine treatment was evaluated by sacral evoked response (SER) and dorsal nerve somatosensory cortical evoked potential (DN-SEP) testings in 15 patients with true premature ejaculation (TPE). We couldn't demonstrate any significant difference between the values of either latency times or amplitudes of the evoked responses determined just before and at the end of the treatment with chlomipramine in these patients. However, the sensory thresholds were 24.4 ± 4.3 V in the pretreatment term and 30.2 ± 7.3 V at the end of the treatment. This difference is statistically significant (P = 0.0031). Our results suggest that chlomipramine increases the sensory threshold for the stimuli in the genital area.

Has anyone ever did these kinds of examinations?
  • Sacral evoked response
  • Dorsal nerve somatosensory cortical evoked potential
What were your results?
Anafranil (Clomipramine) May 2019-October 2021
Lantanon (Mianserin) May 2019-May 2021
Trittico (Trazodone) May 2021-October 2021
Rivotril (Clonazepam) May 2019-present

PSSD since October 2021

Symptoms: low libido and severe ED
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