What do You Guys think about a inhibitor of tryptophan hydroxylase ?

This is a place to post research you have done on the topic along with your conclusions.
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Ghost
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Re: What do You Guys think about a inhibitor of tryptophan hydroxylase ?

Unread post by Ghost »

Flex wrote:Next similair idea:
Effects of Paeonia radix on 5-hydroxytryptamine synthesis and tryptophan hydroxylase expression in the dorsal raphe of exercised rats.
http://www.ncbi.nlm.nih.gov/pubmed/12576675

though Caffeine has the same effects in preventing of exercise depent increase, but this japanese Paeonia does it also in the resting state.

Heres something that affects 5-ht1b and THP2 instead of THP1
The effects of Acorus tatarinowii Schott on 5-HT concentrations, TPH2 and 5-HT1B expression in the dorsal raphe of exercised rats.
http://www.ncbi.nlm.nih.gov/pubmed/25456438

Heres an further altenraitve:
Effects of Phellinus linteus administration on serotonin synthesis in the brain and expression of monocarboxylate transporters in the muscle during exhaustive exercise in rats.
http://www.ncbi.nlm.nih.gov/pubmed/21512297

Caffeine has helped before.

I would appreciate any feedback !
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shineonyou
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Re: What do You Guys think about a inhibitor of tryptophan hydroxylase ?

Unread post by shineonyou »

I can't believe no one has tried it, if the overabundance of synaptic serotonin theory is correct this would be a good way to approach it. Especially considering one of its effects is "vivid sexual stimulation" in sexually deficient males: http://www.ncbi.nlm.nih.gov/pubmed/135926
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