N-AcetylCysteine (NAC): Good or bad?

[tonyareias]

I read about mixed results and opinions but for me 600mg 1h (as needed) before sex improve my erectile function.
Note: I don’t have PSSD, only bad sexual side effects when taking SSRI.

[JakeLawe]

It's good for the liver among other things. I recommend it.

[tonyareias]

N-acetylcysteine improves nitric oxide and α-adrenergic pathways in mesenteric beds of spontaneously hypertensive rats

https://academic.oup.com/ajh/article/16/7/577/189404

In addition to increasing nitric oxide production, NAC can also potentiate the hemodynamic effects of nitric oxide by binding to it and forming a more stable substance, as evident from human studies where NAC treatment significantly enhanced endothelium-dependent vasodilation

https://www.sciencedirect.com/science/a ... 3815495870

NAC also helps to boost nitric oxide production, which can improve your blood flow and lower your heart attack risk. NAC may help to improve fertility in both men and women. One study found that men supplementing with both NAC and selenium experienced an increase in semen quality.

https://www.webmd.com/diet/health-benefits-nac

N-Acetylcysteine (NAC) inhibits renal nitrite and nitrate reabsorption in healthy subjects and in patients undergoing cardiac surgery

https://www.internationaljournalofcardi ... 4/fulltext

N-acetylcysteine inhibits in vivo nitric oxide production by inducible nitric oxide synthase

https://pubmed.ncbi.nlm.nih.gov/11485373/

N-Acetylcysteine Negatively Modulates Nitric Oxide Production in Endotoxin-Treated Rats Through Inhibition of NF-κB Activation

https://www.liebertpub.com/doi/10.1089/ ... 2753625988

[Titeuf]

N-acetylcysteine improves nitric oxide and α-adrenergic pathways in mesenteric beds of spontaneously hypertensive rats

https://academic.oup.com/ajh/article/16/7/577/189404

In addition to increasing nitric oxide production, NAC can also potentiate the hemodynamic effects of nitric oxide by binding to it and forming a more stable substance, as evident from human studies where NAC treatment significantly enhanced endothelium-dependent vasodilation

https://www.sciencedirect.com/science/a ... 3815495870

NAC also helps to boost nitric oxide production, which can improve your blood flow and lower your heart attack risk. NAC may help to improve fertility in both men and women. One study found that men supplementing with both NAC and selenium experienced an increase in semen quality.

https://www.webmd.com/diet/health-benefits-nac

N-Acetylcysteine (NAC) inhibits renal nitrite and nitrate reabsorption in healthy subjects and in patients undergoing cardiac surgery

https://www.internationaljournalofcardi ... 4/fulltext

N-acetylcysteine inhibits in vivo nitric oxide production by inducible nitric oxide synthase

https://pubmed.ncbi.nlm.nih.gov/11485373/

N-Acetylcysteine Negatively Modulates Nitric Oxide Production in Endotoxin-Treated Rats Through Inhibition of NF-κB Activation

https://www.liebertpub.com/doi/10.1089/ ... 2753625988

it's contradictory, studies show that it improves and others are negative

[charles1done]

Hey there! I totally get where you're coming from. I've been using NAC too, and I’ve had similar results. Taking 600mg about an hour before sex really helps improve my erectile function. It’s like a little boost, you know? I’ve read mixed opinions on it as well, but for me, it’s been great in terms of improving performance and overall energy. It's one of those things that works well if you find the right timing and dosage for yourself.

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