Micro dose of clomipramine flipped my PSSD in opposite direction

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Lunchbox634
Posts: 15
Joined: Wed Feb 27, 2019 1:41 pm

Micro dose of clomipramine flipped my PSSD in opposite direction

Unread post by Lunchbox634 »

Hello all. Long time sufferer of pssd from SSRI use. I took just a few grains of powder from a single clomipramine pill. Waited five days to see what changed. And I am 90% happy with the results. Your mileage may vary.

Since SSRI discontinuation, the first two years were the most rough, but I've tried many things and I feel I've recovered about 70%. See my post history if you want to know more.

Erections we're hard to maintain but workable. No urges to have sex. I felt horny occasionally mentally but I'll repeat, never physical urges to have sex. Orgasms were better over time. Needed to watch porn to get off. Extreme kinds of porn. without porn, I suffered from delayed ejaculation. Urinary hesitation. Urinary retention.


Since I took a micro dose of clomipramine and waited for five days for the withdrawal to kick in, things have been so much different.

I no longer need porn to stimulate myself. Delayed ejaculation is gone completely. I dare to say ejaculation comes quickly now. I'm happy with that but I know a lot of men wouldn't like that. Erections are a lot easier to achieve. When I have an erection, I now feel the physical urge to have sex. Something I almost forgot about entirely. I no longer need to relax myself to urinate, no more urinary hesitation. Not sure if urinary retention is gone, but my bladder feels better in general.

I thought of trying this because I read clomipramine can cause premature ejaculation upon discontinuation as a unwanted side effect. Well I thought that is the opposite of how I feel, why not try a small amount and see what happens? Anyways, your mileage may vary and I hope this helps some of us understand more about the situation of PSSD as a whole.
tonyareias
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Joined: Sat Mar 30, 2019 8:02 pm
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Re: Micro dose of clomipramine flipped my PSSD in opposite direction

Unread post by tonyareias »

Micro dosing can help and reverse PSSD as you take it.

From my experience, micro / low SSRI as need or just sometimes are pro erectile / desire. The problem of SSRI is the frequent high dosing.

- Acute SSRI dose improve NO
- Chronic SSRI dose decrease NO
PAT
Posts: 16
Joined: Sun Nov 08, 2020 9:28 pm
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Re: Micro dose of clomipramine flipped my PSSD in opposite direction

Unread post by PAT »

Lunchbox634, glad to hear you are having a positive experience. When you say a few grains of powder - did you dilute them in water first?

Also, I read about your window with Selank. How long did that last for?
cosmo
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Joined: Thu Dec 23, 2021 4:36 pm
Location: Italy
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Re: Micro dose of clomipramine flipped my PSSD in opposite direction

Unread post by cosmo »

happy for you man!
This is very strange compared to my experience.
I took Clomipramine 25 mg for about 2 years and I developed anorgasmia almost immediately. ED started after about 2 years of use. Now it’s 4 months that I don’t take any AD but without any significant improvements (I’ve only regained morning wood).
I think everyone respond very differently to the same medication. This gives my hope that maybe low dose of a different AD could give me some kind of relief but I’m very scared to try anything at this point
Anafranil (Clomipramine) May 2019-October 2021
Lantanon (Mianserin) May 2019-May 2021
Trittico (Trazodone) May 2021-October 2021
Rivotril (Clonazepam) May 2019-present

PSSD since October 2021

Symptoms: low libido and severe ED
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