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Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD
Posted: Sun Sep 12, 2021 1:18 pm
by cdraham
Lol what do you mean with trumps this? So you're not sure which theory pssd is?
Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD
Posted: Sun Sep 12, 2021 1:20 pm
by Area1255_2021
cdraham wrote: ↑Sun Sep 12, 2021 1:18 pm
Lol what do you mean with trumps this? So you're not sure which theory pssd is?
The Nitric Oxide theory applies to all theories/science.
PSSD IS a nitric-oxide issue.
Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD
Posted: Sun Sep 12, 2021 1:21 pm
by cdraham
Area1255_2021 wrote: ↑Sun Sep 12, 2021 1:20 pm
cdraham wrote: ↑Sun Sep 12, 2021 1:18 pm
Lol what do you mean with trumps this? So you're not sure which theory pssd is?
The Nitric Oxide theory applies to all theories/science.
PSSD IS a nitric-oxide issue.
Whats allopregnanolone to do with nitric oxide?
Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD
Posted: Sun Sep 12, 2021 1:23 pm
by Area1255_2021
cdraham wrote: ↑Sun Sep 12, 2021 1:21 pm
Area1255_2021 wrote: ↑Sun Sep 12, 2021 1:20 pm
cdraham wrote: ↑Sun Sep 12, 2021 1:18 pm
Lol what do you mean with trumps this? So you're not sure which theory pssd is?
The Nitric Oxide theory applies to all theories/science.
PSSD IS a nitric-oxide issue.
Whats allopregnanolone to do with nitric oxide?
Because
nitric oxide regulates Allopregnenolone.
Also
it stimulates sex hormones; through Luteinizing Hormone.
Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD
Posted: Sun Sep 12, 2021 1:25 pm
by cdraham
Rodent model of neuropathic pain.. How does this translate to humans
Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD
Posted: Sun Sep 12, 2021 3:24 pm
by Area1255_2021
cdraham wrote: ↑Sun Sep 12, 2021 1:25 pm
Rodent model of neuropathic pain.. How does this translate to humans
Its just the mechanics.
Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD
Posted: Sun Sep 12, 2021 4:11 pm
by cdraham
Area1255_2021 wrote: ↑Sun Sep 12, 2021 3:24 pm
cdraham wrote: ↑Sun Sep 12, 2021 1:25 pm
Rodent model of neuropathic pain.. How does this translate to humans
Its just the mechanics.
I don't rly believe this theory. Makes no sense why people get windows on corticosteroids and antibiotics
Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD
Posted: Mon Sep 13, 2021 5:15 pm
by Delfador
ALLO does not raise gaba, alloi is a modulator of gaba receptor. It binds to the gaba receptor at a different site than gaba does. And most receptor modulators have an inverted U shaped curve of their affinity as agonists with concentration. High allo might inhibit gaba. It's a modulator, not an agonist