Page 2 of 2

Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD

Posted: Sun Sep 12, 2021 1:18 pm
by cdraham
Area1255_2021 wrote: Sat Sep 11, 2021 10:30 pm My Nitric Oxide Theory I think still trumps this but its still *interesting* either way.
Lol what do you mean with trumps this? So you're not sure which theory pssd is?

Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD

Posted: Sun Sep 12, 2021 1:20 pm
by Area1255_2021
cdraham wrote: Sun Sep 12, 2021 1:18 pm
Area1255_2021 wrote: Sat Sep 11, 2021 10:30 pm My Nitric Oxide Theory I think still trumps this but its still *interesting* either way.
Lol what do you mean with trumps this? So you're not sure which theory pssd is?
The Nitric Oxide theory applies to all theories/science. PSSD IS a nitric-oxide issue.

Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD

Posted: Sun Sep 12, 2021 1:21 pm
by cdraham
Area1255_2021 wrote: Sun Sep 12, 2021 1:20 pm
cdraham wrote: Sun Sep 12, 2021 1:18 pm
Area1255_2021 wrote: Sat Sep 11, 2021 10:30 pm My Nitric Oxide Theory I think still trumps this but its still *interesting* either way.
Lol what do you mean with trumps this? So you're not sure which theory pssd is?
The Nitric Oxide theory applies to all theories/science. PSSD IS a nitric-oxide issue.
Whats allopregnanolone to do with nitric oxide?

Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD

Posted: Sun Sep 12, 2021 1:23 pm
by Area1255_2021
cdraham wrote: Sun Sep 12, 2021 1:21 pm
Area1255_2021 wrote: Sun Sep 12, 2021 1:20 pm
cdraham wrote: Sun Sep 12, 2021 1:18 pm

Lol what do you mean with trumps this? So you're not sure which theory pssd is?
The Nitric Oxide theory applies to all theories/science. PSSD IS a nitric-oxide issue.
Whats allopregnanolone to do with nitric oxide?
Because nitric oxide regulates Allopregnenolone.
Also it stimulates sex hormones; through Luteinizing Hormone.

Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD

Posted: Sun Sep 12, 2021 1:25 pm
by cdraham
Area1255_2021 wrote: Sun Sep 12, 2021 1:23 pm
cdraham wrote: Sun Sep 12, 2021 1:21 pm
Area1255_2021 wrote: Sun Sep 12, 2021 1:20 pm

The Nitric Oxide theory applies to all theories/science. PSSD IS a nitric-oxide issue.
Whats allopregnanolone to do with nitric oxide?
Because nitric oxide regulates Allopregnenolone.
Also it stimulates sex hormones; through Luteinizing Hormone.
Rodent model of neuropathic pain.. How does this translate to humans

Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD

Posted: Sun Sep 12, 2021 3:24 pm
by Area1255_2021
cdraham wrote: Sun Sep 12, 2021 1:25 pm
Area1255_2021 wrote: Sun Sep 12, 2021 1:23 pm
cdraham wrote: Sun Sep 12, 2021 1:21 pm

Whats allopregnanolone to do with nitric oxide?
Because nitric oxide regulates Allopregnenolone.
Also it stimulates sex hormones; through Luteinizing Hormone.
Rodent model of neuropathic pain.. How does this translate to humans
Its just the mechanics.

Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD

Posted: Sun Sep 12, 2021 4:11 pm
by cdraham
Area1255_2021 wrote: Sun Sep 12, 2021 3:24 pm
cdraham wrote: Sun Sep 12, 2021 1:25 pm
Rodent model of neuropathic pain.. How does this translate to humans
Its just the mechanics.
I don't rly believe this theory. Makes no sense why people get windows on corticosteroids and antibiotics

Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD

Posted: Mon Sep 13, 2021 5:15 pm
by Delfador
ALLO does not raise gaba, alloi is a modulator of gaba receptor. It binds to the gaba receptor at a different site than gaba does. And most receptor modulators have an inverted U shaped curve of their affinity as agonists with concentration. High allo might inhibit gaba. It's a modulator, not an agonist