Lol what do you mean with trumps this? So you're not sure which theory pssd is?Area1255_2021 wrote: ↑Sat Sep 11, 2021 10:30 pm My Nitric Oxide Theory I think still trumps this but its still *interesting* either way.
Allopregnenolone & Increased GABA-Receptor Theory of PSSD
Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD
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Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD
The Nitric Oxide theory applies to all theories/science. PSSD IS a nitric-oxide issue.cdraham wrote: ↑Sun Sep 12, 2021 1:18 pmLol what do you mean with trumps this? So you're not sure which theory pssd is?Area1255_2021 wrote: ↑Sat Sep 11, 2021 10:30 pm My Nitric Oxide Theory I think still trumps this but its still *interesting* either way.
Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD
Whats allopregnanolone to do with nitric oxide?Area1255_2021 wrote: ↑Sun Sep 12, 2021 1:20 pmThe Nitric Oxide theory applies to all theories/science. PSSD IS a nitric-oxide issue.cdraham wrote: ↑Sun Sep 12, 2021 1:18 pmLol what do you mean with trumps this? So you're not sure which theory pssd is?Area1255_2021 wrote: ↑Sat Sep 11, 2021 10:30 pm My Nitric Oxide Theory I think still trumps this but its still *interesting* either way.
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Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD
Because nitric oxide regulates Allopregnenolone.cdraham wrote: ↑Sun Sep 12, 2021 1:21 pmWhats allopregnanolone to do with nitric oxide?Area1255_2021 wrote: ↑Sun Sep 12, 2021 1:20 pmThe Nitric Oxide theory applies to all theories/science. PSSD IS a nitric-oxide issue.
Also it stimulates sex hormones; through Luteinizing Hormone.
Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD
Rodent model of neuropathic pain.. How does this translate to humansArea1255_2021 wrote: ↑Sun Sep 12, 2021 1:23 pmBecause nitric oxide regulates Allopregnenolone.cdraham wrote: ↑Sun Sep 12, 2021 1:21 pmWhats allopregnanolone to do with nitric oxide?Area1255_2021 wrote: ↑Sun Sep 12, 2021 1:20 pm
The Nitric Oxide theory applies to all theories/science. PSSD IS a nitric-oxide issue.
Also it stimulates sex hormones; through Luteinizing Hormone.
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Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD
Its just the mechanics.cdraham wrote: ↑Sun Sep 12, 2021 1:25 pmRodent model of neuropathic pain.. How does this translate to humansArea1255_2021 wrote: ↑Sun Sep 12, 2021 1:23 pmBecause nitric oxide regulates Allopregnenolone.
Also it stimulates sex hormones; through Luteinizing Hormone.
Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD
I don't rly believe this theory. Makes no sense why people get windows on corticosteroids and antibioticsArea1255_2021 wrote: ↑Sun Sep 12, 2021 3:24 pmIts just the mechanics.cdraham wrote: ↑Sun Sep 12, 2021 1:25 pmRodent model of neuropathic pain.. How does this translate to humansArea1255_2021 wrote: ↑Sun Sep 12, 2021 1:23 pm
Because nitric oxide regulates Allopregnenolone.
Also it stimulates sex hormones; through Luteinizing Hormone.
Re: Allopregnenolone & Increased GABA-Receptor Theory of PSSD
ALLO does not raise gaba, alloi is a modulator of gaba receptor. It binds to the gaba receptor at a different site than gaba does. And most receptor modulators have an inverted U shaped curve of their affinity as agonists with concentration. High allo might inhibit gaba. It's a modulator, not an agonist
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