So weird I was only today reading about a lexapro study and melanocortin. Check this out:anacleta wrote: ↑Wed Jun 03, 2020 8:28 am Hi, I'm f of 32 with pssd from over 6.
in the forum there is the experience of a Bunny girl who had improvements taking Lithium.
Also I am intrigued by Vyleesi that is a drug that acts on melanocortin, recently approved for female hypoxuality of young women. It self-injects itself shortly before the desired effect. A doctor in London said that one of his male patients with PSSD improved immediately after the first injection.
The ability of escitalopram to alter HPA axis reactivity in both control and CeA CRF-OE rats suggests that the control rats were also experiencing elevated stress relative to control subjects in other studies in which the effects of escitalopram are exclusive to the group exposed to stress (Hesketh et al., 2005; Uys et al., 2006). However, escitalopram has previously been demonstrated to decrease expression of proopiomelanocortin (POMC), a precursor to ACTH production, in rats in the absence of stress exposure (Jensen et al., 1999). This supports a role for escitalopram in HPA axis regulation in “control” subjects