alteredhomeostasis - Intro

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alteredhomeostasis
Posts: 196
Joined: Sat Sep 23, 2017 5:21 pm
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alteredhomeostasis - Intro

Unread post by alteredhomeostasis »

Hi everyone,

Lately I've been visiting this forum daily and decided to join and introduce myself.
I'm feeling pretty low right now so I apologize in advance for the unfocused writing.

I took lexapro for about 2 months early in 2017, got sexual dysfunction after about 2 weeks of treatment.
The primary symptom was ED, and a bit of a drop in my libido, but nothing too serious.
I was able to get it up and have satisfactory intercourse using a supplement called steel libido red.
I talked to my psychiatrist about the sexual side effects and she switched me to Vibryyd, which is supposed to have less sexual side effects.
This didn't really help, and the medication is super expensive, so after a few weeks I weaned off of the medication - over a period of about 2 weeks (didn't experience any noticeable withdrawal).

For a few days after I stopped, everything seemed back to normal, then my sexual functioning basically cratered overnight (this was about 4 months ago).
I developed really bad ED, lack of libido, and premature ejaculation.
Its almost impossible to get it up without intense stimulation, and when it does come up I basically need to come immediately. Sometimes the O is okay and other times its garbage.

GInko and SJW worked for a week or two then stopped.

No benefit from MACA, Tribulus, resveratrol, vitamin supplementation.

I took a break for a few weeks and Ginko worked again for about 9 or 10 days (still intensely premature though).

I tried an 18g dose of inositol in early September and woke up at about 3 am with a massive panic attack. That was a bad move. Had a few more panic attacks over the course of the next 2 weeks. Seem to be ok lately though. Interestingly, my libido is a bit better when I've had a few hours of fight or flight.

Anyways, the panic attacks and stress basically have sent me into an intense depression. Have considered jumping from my high rise but I'm not quite there yet. My girlfriend is supportive (for now) .. but I'm afraid that its only a matter of time before she leaves me.

Otherwise - I've noticed that after a dose of NyQuil my symptoms are about 30-40% better. Benadryl on its own is less effective but still does something. Sleep deprivation seems to help, and sleeping more than 7 hours seems to make things worse.

I have a hard time theorizing what happened in my brain. I don't have much hope, but I'm working out and doing yoga.
I'm going to take Viagra tomorrow and hope I can give my girlfriend decent sex.

Anyways,
Thanks for reading,
fablecloth
Posts: 124
Joined: Tue Sep 13, 2016 9:11 am
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Re: Just joined

Unread post by fablecloth »

Hi alteredhomeostasis,

Welcome to the forums.

Thanks for sharing your story with us. Sounds tough, but we know what you're going through.

I'm sad to hear about you wanting to end things, but believe me when I say that things will get better. It just takes time. You owe it to yourself to see things through. We're all in this together, so keep up the faith and don't hesitate to vent here if you need to!
alteredhomeostasis
Posts: 196
Joined: Sat Sep 23, 2017 5:21 pm
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Re: Just joined

Unread post by alteredhomeostasis »

Thanks fablecloth.
I do feel better today, had a couple of drinks last night and was functional enough to have decent sex with my girlfriend this morning.

Regarding the NyQuil, so far it's helped every time I've taken it and my girlfriend has been open to sex.

Otherwise this morning I'm feeling a bit more optimistic about being able to treat pssd. I would love it if more people tried something like TCA+SSRI and then slowly tapering. Or re-instatememt of an SSRI with a different taper schedule. I felt pretty normal after stopping Vibryyd for a few days and do feel like I could potentially experiment with it again and maybe achieve a remisssion of my symptoms. Also I can't help but feel that a lot of people could potentially have ended up with PSSD but instead of dropping the medication just switched around until they found one that alleviated their dysfunction.

If anyone wants to chime in or discuss feel free to reply.
Marksanchez397
Posts: 240
Joined: Fri Jul 24, 2015 3:55 am
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Re: Just joined

Unread post by Marksanchez397 »

alteredhomeostasis wrote:Thanks fablecloth.
I do feel better today, had a couple of drinks last night and was functional enough to have decent sex with my girlfriend this morning.

Regarding the NyQuil, so far it's helped every time I've taken it and my girlfriend has been open to sex.

Otherwise this morning I'm feeling a bit more optimistic about being able to treat pssd. I would love it if more people tried something like TCA+SSRI and then slowly tapering. Or re-instatememt of an SSRI with a different taper schedule. I felt pretty normal after stopping Vibryyd for a few days and do feel like I could potentially experiment with it again and maybe achieve a remisssion of my symptoms. Also I can't help but feel that a lot of people could potentially have ended up with PSSD but instead of dropping the medication just switched around until they found one that alleviated their dysfunction.

If anyone wants to chime in or discuss feel free to reply.
I still can not understand as having all PSSD, some have delayed ejaculation and other premature ejaculation.
I can understand that there are different sexual symptoms with some common symptoms, but it is difficult to understand how different sufferers of this syndrome have two symptoms as completely opposite as these. What could be the explanation?
alteredhomeostasis
Posts: 196
Joined: Sat Sep 23, 2017 5:21 pm
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Re: Just joined

Unread post by alteredhomeostasis »

Hard to say.
Premature ejaculation seems to be more rare than delayed ejaculation.. all I can really chalk it up to is that maybe whatever brain circuit is responsible for orgasm is depleted Serotonergically. My overall feelings are that pssd is a combination of over expression and under expression of serotonin in different brain areas; these may directly cause symptoms or the symptoms could be more downstream - some having to do with dopamine, some with hormones (melanocortins are something I suspect are misregulated).
Imsostupid
Posts: 14
Joined: Tue Aug 17, 2021 3:59 am
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Re: alteredhomeostasis - Intro

Unread post by Imsostupid »

Its weird when my mild pssd started i almost couldnt come.
After crash i developed severe pssd with premature ejaculation
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