PsychoGenesis wrote:i think the pharmacodynamics are even more interesting here, if you read that reddit link again you'll see that the finasteride/nandro combo has exactly the opposite effect
with the supposed AR silencing it gets upregulated slowly then when fina is removed suddenly, AR overexpression and silencing occurs
with the combo it gets downregulated slowly(thanks to nandrolone being one of the most androgenic compounds)
5ar likely becomes upregulated also
then when fina is removed suddenly, all that nandrolone gets converted to DHN which signals the downregulated gene to re-express itself
we are talking at least 4 weeks for the gene expression phase and 2 weeks for the AR re-expression
going to try it after the testosterone trial im doing now
Delving into the sex hormones connection
Re: Delving into the sex hormones connection
Hiwhenn are u planning to try this its intressting
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Re: Delving into the sex hormones connection
next week if everything goes wellpiwomocne wrote:Hiwhenn are u planning to try this its intresstingPsychoGenesis wrote:i think the pharmacodynamics are even more interesting here, if you read that reddit link again you'll see that the finasteride/nandro combo has exactly the opposite effect
with the supposed AR silencing it gets upregulated slowly then when fina is removed suddenly, AR overexpression and silencing occurs
with the combo it gets downregulated slowly(thanks to nandrolone being one of the most androgenic compounds)
5ar likely becomes upregulated also
then when fina is removed suddenly, all that nandrolone gets converted to DHN which signals the downregulated gene to re-express itself
we are talking at least 4 weeks for the gene expression phase and 2 weeks for the AR re-expression
going to try it after the testosterone trial im doing now
Re: Delving into the sex hormones connection
What dosage u planning to do and for how long
PsychoGenesis wrote:next week if everything goes wellpiwomocne wrote:Hiwhenn are u planning to try this its intresstingPsychoGenesis wrote:i think the pharmacodynamics are even more interesting here, if you read that reddit link again you'll see that the finasteride/nandro combo has exactly the opposite effect
with the supposed AR silencing it gets upregulated slowly then when fina is removed suddenly, AR overexpression and silencing occurs
with the combo it gets downregulated slowly(thanks to nandrolone being one of the most androgenic compounds)
5ar likely becomes upregulated also
then when fina is removed suddenly, all that nandrolone gets converted to DHN which signals the downregulated gene to re-express itself
we are talking at least 4 weeks for the gene expression phase and 2 weeks for the AR re-expression
going to try it after the testosterone trial im doing now
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- Joined: Sat Mar 30, 2019 3:15 pm
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Re: Delving into the sex hormones connection
[500-600/wk for 4-6 weeks
today is the second day
today is the second day
Re: Delving into the sex hormones connection
Okey so u only tske nandorolane ore u take finastride too ?
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Re: Delving into the sex hormones connection
taking nandrolone only on this round, first few days i got furious libido / blood filled my dick all day and i masturbated in a day more than the last 2-3 months
mind you i was on testosterone before
mind you i was on testosterone before
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