Delving into the sex hormones connection

This is for hypothesis and even educated speculation.
pii
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Re: Delving into the sex hormones connection

Unread post by pii »

Hiwhenn are u planning to try this its intressting
PsychoGenesis wrote:i think the pharmacodynamics are even more interesting here, if you read that reddit link again you'll see that the finasteride/nandro combo has exactly the opposite effect

with the supposed AR silencing it gets upregulated slowly then when fina is removed suddenly, AR overexpression and silencing occurs

with the combo it gets downregulated slowly(thanks to nandrolone being one of the most androgenic compounds)

5ar likely becomes upregulated also

then when fina is removed suddenly, all that nandrolone gets converted to DHN which signals the downregulated gene to re-express itself


we are talking at least 4 weeks for the gene expression phase and 2 weeks for the AR re-expression

going to try it after the testosterone trial im doing now
PsychoGenesis
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Joined: Sat Mar 30, 2019 3:15 pm
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Re: Delving into the sex hormones connection

Unread post by PsychoGenesis »

piwomocne wrote:Hiwhenn are u planning to try this its intressting
PsychoGenesis wrote:i think the pharmacodynamics are even more interesting here, if you read that reddit link again you'll see that the finasteride/nandro combo has exactly the opposite effect

with the supposed AR silencing it gets upregulated slowly then when fina is removed suddenly, AR overexpression and silencing occurs

with the combo it gets downregulated slowly(thanks to nandrolone being one of the most androgenic compounds)

5ar likely becomes upregulated also

then when fina is removed suddenly, all that nandrolone gets converted to DHN which signals the downregulated gene to re-express itself


we are talking at least 4 weeks for the gene expression phase and 2 weeks for the AR re-expression

going to try it after the testosterone trial im doing now
next week if everything goes well
pii
Posts: 129
Joined: Mon Aug 21, 2017 6:41 pm
Contact:

Re: Delving into the sex hormones connection

Unread post by pii »

What dosage u planning to do and for how long
PsychoGenesis wrote:
piwomocne wrote:Hiwhenn are u planning to try this its intressting
PsychoGenesis wrote:i think the pharmacodynamics are even more interesting here, if you read that reddit link again you'll see that the finasteride/nandro combo has exactly the opposite effect

with the supposed AR silencing it gets upregulated slowly then when fina is removed suddenly, AR overexpression and silencing occurs

with the combo it gets downregulated slowly(thanks to nandrolone being one of the most androgenic compounds)

5ar likely becomes upregulated also

then when fina is removed suddenly, all that nandrolone gets converted to DHN which signals the downregulated gene to re-express itself


we are talking at least 4 weeks for the gene expression phase and 2 weeks for the AR re-expression

going to try it after the testosterone trial im doing now
next week if everything goes well
PsychoGenesis
Posts: 265
Joined: Sat Mar 30, 2019 3:15 pm
Contact:

Re: Delving into the sex hormones connection

Unread post by PsychoGenesis »

[500-600/wk for 4-6 weeks

today is the second day
pii
Posts: 129
Joined: Mon Aug 21, 2017 6:41 pm
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Re: Delving into the sex hormones connection

Unread post by pii »

Okey so u only tske nandorolane ore u take finastride too ?
PsychoGenesis
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Joined: Sat Mar 30, 2019 3:15 pm
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Re: Delving into the sex hormones connection

Unread post by PsychoGenesis »

taking nandrolone only on this round, first few days i got furious libido / blood filled my dick all day and i masturbated in a day more than the last 2-3 months


mind you i was on testosterone before
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