red face is about histamine, if i'm right.HalfPerson wrote: PS: and what is 'serotonin face'? I know I seem to get 'serotonin bad back'. But 'serotonin face'?
Cyproheptadine
Re: Cyproheptadine - serotonin antagonist
Re: Cyproheptadine - serotonin antagonist
Kind of mild MDMA look.
Benefits? None. Sligt euphoria at first (placebo?) then nothing/or worse. I'd rather read Selegiline experiences.
Benefits? None. Sligt euphoria at first (placebo?) then nothing/or worse. I'd rather read Selegiline experiences.
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Re: Cyproheptadine - serotonin antagonist
Foxx wrote:I suspect he would end with more serotonin in the synapse (dilated pupils, serotonin face). 5-ht1a antagonists potentiate ssris. Still, I could be wrong, so pop it and report.
Foxx wrote:Waste of time. Also 5-HT1A antagonist. However it's my (based on experience) opinion.
Foxx wrote:Kind of mild MDMA look.
Benefits? None. Sligt euphoria at first (placebo?) then nothing/or worse. I'd rather read Selegiline experiences.
Fox, doesnt all this things you mention involve 5ht-agonists???
We are talking about an antagonist
Cyproheptadine decreases serotonin in the brain, it is an 5ht1a,5ht2a,... Antagonist.
How should you get dilated pupils or an mdma like effect or a serotonin face with decreased serotonin??
Can someone else put this right?
Re: Cyproheptadine - serotonin antagonist
Just try it out Take two pills (8mg) and tell me what do you feel (except sedation and hunger).
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Re: Cyproheptadine - serotonin antagonist
did it work for anyone ? Iv just been recommended cyproheptadine for PSSD
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Re: Cyproheptadine - serotonin antagonist
No I haven't tried Cyproheptadine, but I tried Mianserin which is similar in terms of serotonin receptor antagonism... Don't be shocked, you will get very drowsy, and be ready for 12 h+ of sleep...the reason for this is the strong H1 antagonism. Somewhere I read that a guy found it helpful for SSRI induced sexual dysfunction...
Last edited by Kinncrimson on Sun Jan 01, 2017 10:50 am, edited 1 time in total.
Re: Cyproheptadine - serotonin antagonist
Cyproheptadine made my testicles bigger and looking pretty healthy, but no help on motivation, sexual arousal etc.
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Re: Cyproheptadine - serotonin antagonist
how long did you take it for and what dose in mg ?nonesuch wrote:Cyproheptadine made my testicles bigger and looking pretty healthy, but no help on motivation, sexual arousal etc.
Re: Cyproheptadine - serotonin antagonist
I've used it off and on but at longest for about 2 months, max dose i used was 8 mg/day. I think 0,5-1 mg is plenty, especially in the beginning, it can be very sedating.
Re: Cyproheptadine - serotonin antagonist
Took a dose last night at 8pm and I'm still drowsy/dopey. Long term use might lead to your brain adjusting its receptors, but I also might lose my job if I take it for more than a week.
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