Studies have shown serotoninergic effects of Oleamide. It makes the 5-HT2A serotonin receptors more sensitive without necessarily influencing the normal signaling process. It also seems to extend the enhanced sensitivity to 5-HT1A and 5-HT2C receptors with no effect on the 5-HT3 receptors and has no effect on serotonin binding to the 5-HT receptors.
Interestingly, Oleamide binds to the 5HT7 receptors and acts as an inhibitor on the 5-HT7 receptor. It acts as agonist on the receptor when no serotonin is present and produces serotonin like effects at a lower intensity.
https://onlinelibrary.wiley.com/doi/pdf ... .0722370.x
OLEAMIDE - Worth Trying?
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OLEAMIDE - Worth Trying?
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Re: OLEAMIDE - Worth Trying?
I was considering it, mostly to help with deep sleep. Apparently it is a CB1 agonist though, which made me reconsider. Not sure how it compares to THC, but I crashed hard after quitting weed at the beginning of the year. Didn't want to ruin any potential recovery I've made in the past 5 months.
https://pubmed.ncbi.nlm.nih.gov/14707029/
https://pubmed.ncbi.nlm.nih.gov/14707029/
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Re: OLEAMIDE - Worth Trying?
I tried oleamide at a dose of about 250 mg. It only gave dreams and some anti-inflammatory properties.
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Re: OLEAMIDE - Worth Trying?
How long did you try it for?AdvencedResearchPL wrote: ↑Sat Jul 31, 2021 10:20 pm I tried oleamide at a dose of about 250 mg. It only gave dreams and some anti-inflammatory properties.
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