Re: desensitization 5ht1a
Posted: Tue Feb 09, 2021 10:12 am
A forum dedicated to collaborative research into PSSD (Post-SSRI Sexual Dysfunction).
https://pssdforum.org/
Yes. Obviously, thinking about PSSD increases anxiety thus sexual dysfunction.JustOnlyHope wrote: ↑Tue Feb 09, 2021 10:12 amWhat do you mean? Psychological thing worse your PSSD?
Thomas wrote: ↑Tue Feb 09, 2021 10:15 amYes. Obviously, thinking about PSSD increases anxiety thus sexual dysfunction.JustOnlyHope wrote: ↑Tue Feb 09, 2021 10:12 amWhat do you mean? Psychological thing worse your PSSD?
I have a baseline with mild PSSD. When I don't feel well (anxiety, lack of sleep, etc.), I am way below my baseline.
What research chems would you recommend to antagonize 5ht1a and upregulate sert, and do you have a site you recommend?Meso wrote: ↑Sat Feb 06, 2021 2:46 pmI crashed from Vortioxetine before. I don't think it's a good idea as it would downregulate 5HT1A receptors too much. Are you off of all drugs now?JustOnlyHope wrote: ↑Sat Feb 06, 2021 2:25 pm My psychiatrist told me it’s good idea to take Vortioxetine but just only 5 mg.
You might be interested in raising SERT and increasing 5HT1A autoreceptors' sensitivity. Cannabigerol (CBG) is a 5HT1A antagonist. Berberine and Evodiamine upregulate SERT, but Berberine has 5-alpha reductase inhibitory effect. Aside from these, there are research chemicals that work the same but more selectively.
In my opinion, it was the Trazodone inducing your symptoms, not the Bupropion, since SRI reinstatement benefited you a little.
I didn't check it. I feel even worse emotionally. I'm afraid it's not going to get better.ErgogenicHealth wrote: ↑Sun Jul 18, 2021 10:40 pmIt will reverse. What about your response to ALCAR?
I crashed from a 5ht1a agonist too and never recovered. What are your symptoms? Do you have any worsening cognitive symptoms?highman wrote: ↑Wed Jul 21, 2021 5:19 pmI didn't check it. I feel even worse emotionally. I'm afraid it's not going to get better.ErgogenicHealth wrote: ↑Sun Jul 18, 2021 10:40 pmIt will reverse. What about your response to ALCAR?
I feel more tired and depressed. Erections are very weak after this.Tree wrote: ↑Wed Jul 21, 2021 8:46 pmI crashed from a 5ht1a agonist too and never recovered. What are your symptoms? Do you have any worsening cognitive symptoms?highman wrote: ↑Wed Jul 21, 2021 5:19 pmI didn't check it. I feel even worse emotionally. I'm afraid it's not going to get better.ErgogenicHealth wrote: ↑Sun Jul 18, 2021 10:40 pm
It will reverse. What about your response to ALCAR?