Be super careful with TREN.... You're aware of all the risks right?

1. Please respect others. No one wants to be here, everyone has their reason. We dont limit access to people that got issues from ssri’s only. 2. I dont see how these theories (serotonin, 5ht1a related) are not potentially relevant to the pssd community. Although most will turn out to be faulty, th...

Background NLX-101 (also known as F15599) is a highly selective and efficacious ‘biased’ agonist at cortical 5-hydroxytryptamine 1A (5-HT 1A ) heteroreceptors. In rodents, it possesses marked antidepressant-like activity, potently and completely abolishing immobility in the forced swim test (FST) wi...

Feverfew is a 5-HT2A antagonist. So is cyproheptadine. Have you ever tried Cyproheptadine?

I will need to order some of this (Somewhere?) to trial.

This ISSM Webinar is on Post SSRI Sexual Dysfunction. The webinar will be opened by Annamaria Giraldi, ISSM President (Denmark). The webinar will be moderated by Alan Shindel (USA) and Marco Gonçalves (Portugal). Topics: Post-SSRI Sexual Dysfunction (PSSD): history and relevance – David Healy (Repub...

NAC destroys my emotions and pleasure response too. Stay away. You will return back to baseline soon.

Male rats lacking the serotonin transporter (SERT–/–) display a robust genotype that has a lower basal ejaculatory performance than wildtype rats (SERT+/+) or heterozygous serotonin transporter knockout (SERT+/–) rats (Chan et al., 2011; Esquivel-Franco et al., 2018). More specific, due to the lack ...

BIMT 17, the only compound reported to be a full 5-HT1A agonist and a 5-HT2A antagonist at the frontal cortex, was assessed in three animal paradigms sensitive to antidepressants in rats: olfactory bulbectomy (OB), differential-reinforcement-of-low rate 72-s (DRL 72-s) and learned helplessness (LH)....

highman wrote: ↑Sun Jul 18, 2021 8:43 am Hi,

Berberine works on 5HT1a receptors right? After use this my erection is worst It's not full. It's chance to reverse this?

It will reverse. What about your response to ALCAR?