Search found 25 matches

by Youcanwin
Mon Aug 23, 2021 3:44 pm
Forum: General
Topic: Enzyme question progesterone allopreg 3α-Hydroxysteroid dehydrogenase
Replies: 14
Views: 1871

Re: Enzyme question progesterone allopreg 3α-Hydroxysteroid dehydrogenase

Certainly agree with some things, disagree with others. You are correct in thinking that Allopregnanlone may indeed not be high, but success with Ultra Hard certainly shows. As for methylation, there is no doubt that androgens are methylated, but they are not the only thing to be methylated. PSSD is...
by Youcanwin
Mon Aug 23, 2021 3:07 pm
Forum: General
Topic: Enzyme question progesterone allopreg 3α-Hydroxysteroid dehydrogenase
Replies: 14
Views: 1871

Re: Enzyme question progesterone allopreg 3α-Hydroxysteroid dehydrogenase

Brother, how can I contact you? This is one of the most credible theories. As Propecia alters levels of neurosteroids and behaves in an anti-androgen manner similarly, antidepressants do the same, albeit through a different pathway. They are both anti-androgens at the end of the day, and explains wh...
by Youcanwin
Mon Aug 23, 2021 11:53 am
Forum: General
Topic: Enzyme question progesterone allopreg 3α-Hydroxysteroid dehydrogenase
Replies: 14
Views: 1871

Re: Enzyme question progesterone allopreg 3α-Hydroxysteroid dehydrogenase

You’re on the right track, in my opinion. The real cause of PSSD is caused by alterations to 3a-HSD. There is no doubt at this point, that PSSD is caused by methylated sex hormones and neurosteroids. I will try to find the answer to this. Anybody who thinks 5HT1A receptors are involved in PSSD need ...
by Youcanwin
Fri Aug 13, 2021 7:58 pm
Forum: Treatments and experimentation
Topic: Ultra Hard by Iconic Formulations
Replies: 3
Views: 1004

Re: Ultra Hard by Iconic Formulations

I will, but find struggles to get it where I am right now as I will be traveling. If anyone does try it, let me know.
by Youcanwin
Fri Aug 13, 2021 7:24 pm
Forum: Treatments and experimentation
Topic: Ultra Hard by Iconic Formulations
Replies: 3
Views: 1004

Re: Ultra Hard by Iconic Formulations

Is nobody willing to try this?
by Youcanwin
Fri Aug 13, 2021 2:49 pm
Forum: Treatments and experimentation
Topic: Is NLX-101 A New Drug To Explore In PSSD?
Replies: 5
Views: 1245

Re: Is NLX-101 A New Drug To Explore In PSSD?

Man, sorry. I do not think you have PSSD. Attempts in playing around with St. John Wort, Inositol have really yielded no real results. It’s clear you have what you describe, but it has nothing to do with PSSD. There is a clear and obvious dysfunction in our androgen system, of which you exhibit no s...
by Youcanwin
Wed Aug 11, 2021 3:50 pm
Forum: Treatments and experimentation
Topic: Ultra Hard by Iconic Formulations
Replies: 3
Views: 1004

Ultra Hard by Iconic Formulations

Has anyone tried Ultra Hard by Iconic Formulations? Trazohell (RIP) had a great window on this. @Meso What do you think of this (Androsterone + Epiandrosterone)? It antagonizes GABA receptors, which should help PSSD, no? It can also up-regulate androgen receptors? Doesn’t seem like a good fit for Po...
by Youcanwin
Sat Aug 07, 2021 11:09 pm
Forum: General
Topic: Raising Money to Cure PSSD
Replies: 10
Views: 2026

Raising Money to Cure PSSD

Hypothetically, if we could raise money to cure PSSD as an epigenetic illness - how much money would we need to fully fund enough research to understand and cure the condition?
10 million? 20 million?
by Youcanwin
Fri Aug 06, 2021 3:55 pm
Forum: Treatments and experimentation
Topic: How to manage insulin resistance
Replies: 9
Views: 2018

Re: How to manage insulin resistance

Hello, TalkingAnt. Can I speak with you man?