Could 5HT receptor agonists maybe activate/resensitize 5HT receptors? A few days ago I found this Wikipedia article: https://en.m.wikipedia.org/wiki/5-HT2C_receptor_agonist. It says that 5HT agonists (in general, although I could only find an article in 5ht2c agonists) could be involved in helping w...

Wellbutrin update: The positive effect on genital sensitivity and libido has vanished. Everything is back to the “pre Wellbutrin” level. :( Still, it was so good to experience how beautiful sexuality can be after 10 “numb years”. Edit (March 1, 2019): When I upped the dose to 300mg, all the positive...

Although I wouldn’t recommend to stop Escitalopram right away, I cannot support the idea that tapering slowly is of any use with regards to pssd. I tapered off very slowly because I took ssri for an eating disorder and wanted to make sure the symptoms don’t return and I still got pssd.

@Halan I just read that you are interested in fluoxetine. Although your post is from August 7, I would like to say something about fluoxetine. I can absolutely NOT recommend anybody try fluoxetine (except maybe for lowdosing). Fluoxetine gave me very severe PSSD although I tapered off VERY (not to s...

Hi everybody, this post is addressed to all German members who haven’t reported their case to the BfArM (Bundesinstitut für Arzneimittel). If you haven’t done so or know someone who suffers from PSSD and hasn’t reported their case to the BfArM, please do so/encourage them to do so. For the report yo...

Wellbutrin is marketed as Elontril in Germany. The regular dose for an adult is 300mg (starting with 150mg). However, Elontril are controlled-release tablets/Tablets with modified drug release (“Retardtabletten”) and there is an explicit warning in the leaflet not to split the pills because this wou...

@bunny and North4: I understand your thoughts. I, myself, am very surprised. But I can feel the effect every day. I take the pill early in the morning and then the “feeling” somehow increases throughout the day. However, I am still not convinced that this effect is permanent. And because of my “fluo...

Hi hs1312, I’m female, so I don’t get morning erections. But I guess if I was male I definitely would. My libido and sensitivity are at pre-pssd level. I haven’t felt anything like this in 10 (!) years. It is very surprising to me. And I am not the placebo-type of person who feels something from a c...

It’s me again. Just wanted to let you know that the very (!) positive effect of Wellbutrin on libido and genital sensitivity is still there. I’m on day 18 now and I can definitely say that my libido has increased from maybe 5% (if at all) to 100%. Genital sensitivity is also so much better. I am so ...

I just wanted to let you know that I’ve been taking Wellbutrin 150mg for 10 days now and I’m seeing a tremendous increase in libido. I felt some slight changes on day three but wasn’t sure if this was just placebo. But I’ve had several days in one week now with significantly increased libido. And to...