Search found 49 matches

by Dubya_B
Tue Jul 04, 2017 7:01 pm
Forum: General
Topic: Long term SSRI use lowers neurosteroid levels
Replies: 18
Views: 5900

Re: Long term SSRI use lower Neurosteroid levels

Good stuff!

Are any of you guys signing up for the University of Milan study of PSSD to see if lowered neurosteroid levels are part of the condition?
by Dubya_B
Sat Jun 10, 2017 1:16 am
Forum: PSSD related research
Topic: 13-cis-Retinoic Acid (Accutane)
Replies: 34
Views: 17524

Re: 13-cis-Retinoic Acid (Accutane)

I wanted ask you once...are there any recoveries from post accutane? There seem to be quite a few recoveries from physical side effects of Accutane, such as bowel and digestive problems, dry skin and eyes, and joint pains. On the other hand, the people with sexual and mental side effects after Accu...
by Dubya_B
Wed Jun 07, 2017 1:11 am
Forum: PSSD related research
Topic: 13-cis-Retinoic Acid (Accutane)
Replies: 34
Views: 17524

Re: 13-cis-Retinoic Acid (Accutane)

Yea I'd never suggest anyone starting it, I was just so intrigued by how specific it was to some of the brain regions we focus on. However, if anyone has tried it, I'd be curious to see what happened. In the same way, if it does do permanent damage in that way, then maybe an SSRI would be something...
by Dubya_B
Fri May 12, 2017 12:28 am
Forum: PSSD related research
Topic: 5α-Reductase / PFS connections Research
Replies: 21
Views: 7211

Re: 5α-Reductase / PFS connections Research

Thanks Ghost. My schooling is over until June, so I finally have time to spend dealing with this atrocity. Planning on elaborating more on some of these studies on the LastingSides site over the next month. btw- Kudos to you for going into the medical field! Surprising that more people who were scre...
by Dubya_B
Thu May 11, 2017 11:02 pm
Forum: PSSD related research
Topic: 5α-Reductase / PFS connections Research
Replies: 21
Views: 7211

Re: 5α-Reductase / PFS connections Research

NEUROSTEROID LEVELS IN MULTIPLE SCLEROSIS PATIENTS: D. Caruso et al., “Neuroactive steroid levels in plasma and cerebrospinal fluid of male multiple sclerosis patients,” Journal of Neurochemistry, vol. 130, no. 4, pp. 591–597, Aug. 2014. http://onlinelibrary.wiley.com/doi/10.1111/jnc.12745/abstract...
by Dubya_B
Sat May 06, 2017 2:08 pm
Forum: PSSD related research
Topic: 5α-Reductase / PFS connections Research
Replies: 21
Views: 7211

Re: 5α-Reductase / PFS connections Research

Thanks for posting that Ghost! I have a few collections of similarly related studies. NEUROSTEROIDS: Miscellaneous information concerning neurosteroid synthesis and physiological/psychological effects. DHT, T, estrogens, progestins, and DHEA as neurosteroids are included. J. M. Torres and E. Ortega,...
by Dubya_B
Wed Apr 26, 2017 2:32 am
Forum: Non-SSRI sexual dysfunction
Topic: Lasting Side Effects Website
Replies: 3
Views: 9584

Lasting Side Effects Website

Hello all, In the past several years there has been a noticeable increase in the recognition of PSSD, Post-Finasteride Syndrome, and Post-Acctuane Sexual Dysfunction. There has also been a rise in intercommunication among our patient groups, with a clear overlap in our most common and persistent sym...
by Dubya_B
Mon Apr 17, 2017 12:24 am
Forum: General
Topic: Progesterone, 17- Oh progesterone, Androstenedione
Replies: 209
Views: 51396

Re: Progesterone, 17- Oh progesterone, Androstenedione

Abstract of the Milan/Melcagni PFS Neurosteroids study. It appears to not be officially published yet: Melcangi, Roberto Cosimo et al. “ NEUROACTIVE STEROID LEVELS AND PSYCHIATRIC AND ANDROLOGICAL FEATURES IN POST-FINASTERIDE PATIENTS .” The Journal of Steroid Biochemistry and Molecular Biology http...
by Dubya_B
Tue May 10, 2016 2:24 pm
Forum: PSSD related research
Topic: SSRI and Neurosteroids!
Replies: 11
Views: 10580

Re: SSRI and Neurosteroids!

Hello everyone. Glad to see the PSSD forum has been reborn since the days of forum-motion. I am a 17-year sufferer of post-Accutane sexual dysfunction and severe anhedonia who has noticed many PSSD, PFS, and post-Accutane patients suffer identical symptoms. ...Not just simple ED, but severe genital ...