Search found 204 matches

by DrugsAreBad
Thu Aug 30, 2018 3:58 am
Forum: PSSD related research
Topic: PSSD Genome Project [Megathread]
Replies: 320
Views: 305038

Re: PSSD Genome Project [Megathread]

Ghost, I can only speculate as to why people aren't donating. As for myself, I haven't taken the test and I believe you disqualified me since I didn't use an SSRI. I suppose I could take it anyway, but I agree with your reasoning. This is complicated enough without widening the scope. I suspect many...
by DrugsAreBad
Wed Aug 29, 2018 5:54 pm
Forum: General
Topic: What for healing ED?
Replies: 13
Views: 5223

Re: What for healing ED?

It's interesting that user continue mentions improvements from chocolate, since chocolate lowers cortisol [1] [2].

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350893/
2. http://www.pssdforum.com/viewtopic.php?f=22&t=2295
by DrugsAreBad
Wed Aug 29, 2018 3:40 pm
Forum: Treatments and experimentation
Topic: Elevated creatine kinase and leukocyte count
Replies: 0
Views: 3350

Elevated creatine kinase and leukocyte count

I had a test done of most of my hormones and found two of them were elevated: creatine kinase and leukocyte count. This may indicate high levels of serotonin. There is no specific test for serotonin syndrome. An elevation of the total creatine kinase and leukocyte count and elevated transaminase lev...
by DrugsAreBad
Wed Aug 29, 2018 7:47 am
Forum: Treatments and experimentation
Topic: Ibogaine
Replies: 52
Views: 18894

Re: Ibogaine

Indeed. I'm watching this with great interest. I've been meaning to try Iboga for a long time, but I can't seem to get ahold of it where I live.
by DrugsAreBad
Wed Aug 29, 2018 7:46 am
Forum: Speculations and hypotheses
Topic: Identifying relevant substances
Replies: 4
Views: 4766

Re: Identifying relevant substances

Thanks Jaxx. I haven't measured my cortisol levels, but I'll see if I can get it done and report if I have any relevant info.
by DrugsAreBad
Wed Aug 29, 2018 4:12 am
Forum: Speculations and hypotheses
Topic: Identifying relevant substances
Replies: 4
Views: 4766

Identifying relevant substances

Background The body is constantly striving to balance its levels of various substances by keeping them within certain bounds. For many substances, this balancing by up- and down regulation happens on a perceptible time scale of days to weeks and explains why the introduction of a substance has a ce...
by DrugsAreBad
Wed Aug 29, 2018 2:44 am
Forum: Speculations and hypotheses
Topic: Glucocorticoid receptors
Replies: 13
Views: 8267

Re: Glucocorticoid receptors

Very interesting post, TalkingAntColony. Adding to this, some people have had positive results with Inositol, which is apparently affected by Lithium and somehow related to cortisol levels. Lithium treatment has been found to inhibit the enzyme inositol monophosphatase, involved in degrading inosito...
by DrugsAreBad
Sat Aug 25, 2018 2:37 am
Forum: Treatments and experimentation
Topic: Inositol dosage and timing
Replies: 0
Views: 3848

Inositol dosage and timing

I've been experimenting with Inositol for about two weeks now. I haven't figured it out completely, but I've noticed a few things: (1) different amounts have opposite effects (2) the immediate and lasting effects are different An amount around 1000 mg makes me sluggish, gives me a blunted affect and...
by DrugsAreBad
Sun Aug 19, 2018 1:01 pm
Forum: Speculations and hypotheses
Topic: Accounts of Inositol also mention other chemicals
Replies: 4
Views: 6389

Accounts of Inositol also mention other chemicals

There are two accounts of successful recoveries using inositol. But both users also mention other substances in combination with Inositol, Berebine and Crystal Light. Berebine I can't find much about the effects of Berebine, other than it being an alkaloid derived from tyrosine. Speculative connecti...
by DrugsAreBad
Sun Aug 19, 2018 7:49 am
Forum: Speculations and hypotheses
Topic: Could PSSD have a psychological solution?
Replies: 5
Views: 6035

Re: Could PSSD have a psychological solution?

It's important to exclude psychological cause, because if there are any and they are related to our problem, we could jump into an obsessive loop we won't get out of. Very true, but I'd like to take this one step further. Due to the apparent interplay between brain chemistry and what we call psycho...