Search found 111 matches
- Mon Nov 13, 2023 6:35 am
- Forum: General
- Topic: Naltrexone was the only thing that helped me at all
- Replies: 71
- Views: 46061
Re: Naltrexone was the only thing that helped me at all
Everything improved.
- Sat Nov 11, 2023 5:44 pm
- Forum: General
- Topic: Study: Endorphins in Male Impotence: Evidence for Naltrexone Stimulation of Erectile Activity in Patient Therapy
- Replies: 9
- Views: 15768
Study: Endorphins in Male Impotence: Evidence for Naltrexone Stimulation of Erectile Activity in Patient Therapy
Abstract In the present study we evaluated whether naltrexone administration could stimulate sexual function in 30 male patients, ages 25 to 50 years, with idiopathic impotence of at least one year's duration and not of organic etiology. The patients received naltrexone (50 mg/day) or placebo, on a ...
- Sat Nov 11, 2023 5:11 pm
- Forum: General
- Topic: Chronic Administration of Naltrexone Upregulates Opioid Receptors
- Replies: 0
- Views: 16179
Chronic Administration of Naltrexone Upregulates Opioid Receptors
Here’s more discussion on the Wikipedia page explaining that prolonged use of naltrexone has been observed to increase opioid receptors. Based on available evidence, naltrexone seems to have minimal untoward effects in the aforementioned areas, at least with long-term therapy, .[45][46][47][48] It h...
- Sat Nov 11, 2023 8:05 am
- Forum: General
- Topic: Naltrexone was the only thing that helped me at all
- Replies: 71
- Views: 46061
Re: Naltrexone was the only thing that helped me at all
Not that I noticed at all.
- Thu Nov 09, 2023 4:25 pm
- Forum: General
- Topic: Naltrexone was the only thing that helped me at all
- Replies: 71
- Views: 46061
Re: Naltrexone was the only thing that helped me at all
Please read the Wikipedia entry on the pharmacology behind Naltrexone’s mechanism of action; here is part of it, maybe it’s relevant. Naltrexone and its active metabolite 6β-naltrexol are competitive antagonists of the opioid receptors.[77][78] Naltrexone is specifically an antagonist preferentially...
- Thu Nov 09, 2023 4:21 pm
- Forum: General
- Topic: Naltrexone was the only thing that helped me at all
- Replies: 71
- Views: 46061
Re: Naltrexone was the only thing that helped me at all
Why do you say conversely? Don’t they both significantly involve opioid receptors (specifically the MOR)?
- Thu Nov 09, 2023 12:45 pm
- Forum: General
- Topic: What can I take for social anxiety?
- Replies: 1
- Views: 10344
Re: What can I take for social anxiety?
Alliant hemp sells extremely cheap cbd oil- they have a bottle of 24,000 mg cbd with a cbd/thc ratio of 100:1. I didn’t know anything about cbd oil until recently, but I tried it and it works really well- just 20-50 mg is perfect for me.
- Fri Nov 03, 2023 5:21 pm
- Forum: General
- Topic: Naltrexone was the only thing that helped me at all
- Replies: 71
- Views: 46061
Re: Naltrexone was the only thing that helped me at all
My pssd was caused by a combination of an ssri and lamictal. I took around 12.5 mg maybe twice a week for a couple of months (it’s in my post history).
- Fri Nov 03, 2023 5:17 pm
- Forum: General
- Topic: If you don’t have the courage to try something new, you’re probably going to have PSSD a lot longer
- Replies: 6
- Views: 12608
Re: If you don’t have the courage to try something new, you’re probably going to have PSSD a lot longer
I appreciate your comment! I’m just frustrated because I feel like I’m shouting into a void, and I’m quite certain some people would be significantly helped by this. Im sorry that you couldn’t take it. I wish you the best in your recovery and in life!
- Fri Nov 03, 2023 3:14 pm
- Forum: General
- Topic: If you don’t have the courage to try something new, you’re probably going to have PSSD a lot longer
- Replies: 6
- Views: 12608
If you don’t have the courage to try something new, you’re probably going to have PSSD a lot longer
I’ve made several posts now detailing just how much Naltrexone has permanently improved my PSSD. I’ve explained how it got worse immediately before taking a week or so to improve, and that the improvements largely stuck. I know there are thousands of you on here that read these posts daily waiting f...