Search found 39 matches

by ssinus
Sat Sep 09, 2023 6:14 pm
Forum: General
Topic: Is Low Dose Naltrexone safe for us?
Replies: 1
Views: 4980

Re: Is Low Dose Naltrexone safe for us?

Hey, I tried it in the past - I read a lot of reports from people who took it, most of them were positive, so I gave it a shot - unfortunately it was disaster for me. I took first dose LDN (dissolved in solution - 4mg if Im not mistaken) before bed - in the middle of the night I woke up from nightma...
by ssinus
Sat May 28, 2022 7:34 am
Forum: General
Topic: Please AVOID doing weed/cannabis/THC
Replies: 16
Views: 15480

Re: Please AVOID doing weed/cannabis/THC

I don't know how THC PAWS is mediated. If it's receptor desensitization, then maybe CBD/CBG can help since they are weak eCB receptors antagonists. Also, generally speaking, people who suffer from depersonalization/derealization use Naltrexone to try and cure these symptoms. I don't know how much t...
by ssinus
Fri May 08, 2020 6:39 pm
Forum: New Member Intros
Topic: Varicocele-guy introduction and a possible breakthrough - Normal dose naltrexone
Replies: 21
Views: 8270

Re: Varicocele-guy introduction and a possible breakthrough - Normal dose naltrexone

3 weeks passed since I tried a low dose naltrexone (LDN) for just a 2 days, 1,5mg and 2mg before bed. In such a low dose and just for 2 days (finished right after) it gaves me tinitus and trouble of sleeping - I thought it will go away eventually but this shit still bothers me. I tried zinc and gink...
by ssinus
Mon Oct 22, 2018 8:19 pm
Forum: PSSD related research
Topic: New study reveals the epigenetic effects of Citalopram
Replies: 95
Views: 29856

Re: New study reveals the epigenetic effects of Citalopram

approx 6 years ago or so when the paxilprogress.org website was still active I had my own "introduction" thread where PSSD guy from Poland responded on my comments, he mentioned that his parents were the owners of some local pharmacy so he had access to a lot of stuff to try, he mentioned ...
by ssinus
Fri Feb 16, 2018 7:28 am
Forum: Treatments and experimentation
Topic: Low Dose SSRI (Reinstatement)
Replies: 515
Views: 200615

Re: low dose ssri

Im almost a week since mentioned dosage and erection problems still persist. Another interesting thing is that among the PSSD I suffered with severe lower back pain for approx a year which is after this low dosage totally gone, I mean totally. I dont think this is SERT inhibition related nor neurost...
by ssinus
Wed Feb 14, 2018 5:25 am
Forum: Treatments and experimentation
Topic: Low Dose SSRI (Reinstatement)
Replies: 515
Views: 200615

Re: low dose ssri

2bb52174afccc.png Im in a 5th day since I took tiny 0.3 mg dose (1 bead) and things are just getting worse - mainly with genital numbness - this is crazy. How the f..k is this possible with just a tiny dose, as I already mentioned it shouldn't saturated that much transporters, as you could see also...
by ssinus
Sun Feb 11, 2018 6:15 am
Forum: Treatments and experimentation
Topic: Low Dose SSRI (Reinstatement)
Replies: 515
Views: 200615

Re: low dose ssri

2 days ago I tried a low dose of venlafaxine - tiny dose just a 1 bead from the 75 mg capsule which is approx. 0.3 mg. I took it in the evening before bed and next morning I woke up with a significant worsening of the genital anesthesia. What the hell is going on here with this damn PSSD, this tiny ...
by ssinus
Fri Dec 08, 2017 7:41 am
Forum: Treatments and experimentation
Topic: Low Dose SSRI (Reinstatement)
Replies: 515
Views: 200615

Re: low dose ssri

^Yes. Something is shut down, and I think that it involves the HPA axis. Whatever it takes to get that going again is what we are looking for. The thing that it involves HPA is known from the beginning, problem is that it is not just that but more complex group of things which are connected, but I ...
by ssinus
Thu Dec 07, 2017 3:56 pm
Forum: Treatments and experimentation
Topic: Low Dose SSRI (Reinstatement)
Replies: 515
Views: 200615

Re: low dose ssri

Coraggio wrote:Quote. I wish to know the same. Low dosing should show its effect after some weeks. If doesn' t arrive increase slowly the dose and let see
Oh really ? Have you tried it by yourself ???
by ssinus
Tue Dec 05, 2017 7:15 pm
Forum: General
Topic: PSSD Symptoms (Official Thread)
Replies: 453
Views: 165415

Re: Do you experience genital shrinkage?

this is one of the worst symptoms for me as well. Any sort of intense activity just worsen this condition. What I found during the years of suffering to help a bit is workout/weight lifting so that you force your body to produce more hgh, but during the exercise it is a real fight with this hellish ...