MAY 20, 2024 - FDA Sued Over Inaction on Citizen Petition: Drugs Have Been Linked to Long-Term Sexual Dysfunction https://www.citizen.org/news/fda-sued-over-inaction-on-citizen-petition/ Some media have begun to talk about it and hopefully more will come. If you have something to say, now is the tim...

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Thanks, that's interesting! It gives us hope! That said, PIEZO2 might not be involved in the pleasure of sensations : In clinical evaluations and surveys, three men and two women with PIEZO2-deficiency syndrome reported severe hyposensitivity in genital sensation. Despite their marked mechanosensor...

The Form and Function of PIEZO2 (2021) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794004/ "Given that PIEZO2 has several physiological roles, even if selective agonists and/or antagonists are identified, systemic drug delivery methods may not safely treat a single function in isolation. Inco...

from a previous article: "PIEZO2 function is needed for triggering a touch-evoked erection reflex and successful mating in both male and female mice. Humans with complete loss of PIEZO2 function have genital hyposensitivity and experience no direct pleasure from gentle touch or vibration" ...

Patients with PSSD show on average high rates of genital fibrosis, or scar tissue, which can cause or worsen symptoms of erectile dysfunction and genital numbness. Clinical studies on patients with PSSD about it: - Waldinger MD, van Coevorden RS, Schweitzer DH, Georgiadis J. Penile anesthesia in Pos...

Dr Kenneth M Peters, urologist at Beaumont Hospital, Royal Oak, Michigan, on 23 February 2024 anticipates the results of a forthcoming study on Twitter https://twitter.com/KennethMPeters1/status/1761131131376681245 NM094 | POST-RETINOID, POST-FINASTERIDE AND POST-SSRI SYNDROMES: PATIENT EVALUATION A...

Frontiers in Neuroendocrinology Available online 21 November 2023, 101114 POST-FINASTERIDE SYNDROME AND POST-SSRI SEXUAL DYSFUNCTION: TWO CLINICAL CONDITIONS APPARENTLY DISTANT, BUT VERY CLOSE Silvia Giatti, Silvia Diviccaro, Lucia Cioffi, Roberto Cosimo Melcangi Dipartimento di Scienze Farmacologic...

Frequency of self-reported persistent post-treatment genital hypesthesia among past antidepressant users: a cross-sectional survey of sexual and gender minority youth in Canada and the US AUTHORS Yassie Pirani Jorge Andres Delgado-Ron Pedro Marino Dr. Amit Gupta Emily Gray Sarah Watt Kinnon R MacKin...