Search found 217 matches
- Wed Feb 14, 2018 2:57 am
- Forum: General
- Topic: Valproate acid
- Replies: 27
- Views: 6662
Re: Valproate acid
I was reacently reading about Valproaic acid on gene expression. It is potent active demethylation agent trough HDAC inhibiton https://www.ncbi.nlm.nih.gov/pmc/articles/PMC125788/ https://www.ncbi.nlm.nih.gov/pubmed/12748177 http://www.pnas.org/content/105/36/13614.full It can also induce neuroplas...
- Sun Feb 11, 2018 4:30 pm
- Forum: Treatments and experimentation
- Topic: Low Dose SSRI (Reinstatement)
- Replies: 515
- Views: 204434
Re: low dose ssri
We are a kind of iatrogen autistic like people, and we have depleted both serotonin and gaba neurotransmission.
- Mon Jan 22, 2018 4:00 am
- Forum: General
- Topic: I overcame PSSD with pure dedicaton!!!
- Replies: 10
- Views: 4225
Re: I overcame PSSD with pure dedicaton!!!
Great Man!! Your words give us a lot of hope. Thank you so much. I hope you will be here every now and to support guys they want follow your steps (like me).
- Sat Jan 20, 2018 5:04 pm
- Forum: General
- Topic: Symptoms become a lot better when I have the flu
- Replies: 24
- Views: 6261
Re: Symptoms become a lot better when I have the flu
I think you are right. Maybe also because TNF-alpha acutely activates SERT function.
- Sat Jan 20, 2018 2:03 pm
- Forum: Speculations and hypotheses
- Topic: 5-ht theory and steroidogenesis [Coraggio's corner]
- Replies: 83
- Views: 32276
Re: 5-ht theory and steroidogenesis
I think I have found the final lick to understand the situation 1. First article: https://www.ncbi.nlm.nih.gov/m/pubmed/15936112/ "Serotonergic 5-HT2A receptor stimulation induces steroid 5alpha-reductase gene expression in rat C6 glioma cells via transcription factor Egr-1. Morita K, et al. B...
- Fri Jan 19, 2018 10:09 am
- Forum: PSSD related research
- Topic: Read this if you want to end PSSD for good
- Replies: 12
- Views: 6091
Re: Read this if you want to end PSSD for good
Done. Thanks for the organization.
OT: I am going to update soon about Melcangi.
OT: I am going to update soon about Melcangi.
- Sat Jan 13, 2018 1:35 pm
- Forum: General
- Topic: Brain Food Nutrition
- Replies: 4
- Views: 2659
Re: Brain Food Nutrition
Intermittent fasting
- Wed Dec 27, 2017 1:57 pm
- Forum: New Member Intros
- Topic: Dryed Intro
- Replies: 16
- Views: 5263
Re: I'm new 9 days on paxil
Listen what Ghost has told you! Do it! Go to your doctor, take the prescription and run to buy the liquid and then taper off very gently. I want to understand better:why do you have decided to cold turkey only after 9 days? How much there were your sexual symptoms? And now after cold turkey your sym...
- Sun Dec 24, 2017 12:01 pm
- Forum: Treatments and experimentation
- Topic: L-Cysteine and L-Histidine
- Replies: 72
- Views: 21262
Re: L-Cysteine and L-Histidine
And also DOLT once mentioned that there are no endorphine like feeling after exercises, but i found that the only thing that can help with it is 10 km fast walk on hill(at least for me) I have started training in July almost every day. i do running, cycling, swimming and playnig sports. Now I have ...
- Thu Dec 21, 2017 2:49 am
- Forum: Treatments and experimentation
- Topic: L-Cysteine and L-Histidine
- Replies: 72
- Views: 21262
Re: L-Cysteine and L-Histidine
Interesting, I m going to look it into..