Search found 92 matches

by Determined-Mind
Thu Apr 25, 2024 4:06 pm
Forum: New Member Intros
Topic: PSSD research - Intro
Replies: 2
Views: 219

Re: PSSD research - Intro

Welcome to the forum! What drug combinations help you have better orgasms? Which treatments have helped you with which symptoms? Did your anhedonia affect other parts of your body besides sex? Nipples? Thighs, belly, arms, back? Do you feel emotions of love? Emotional excitement over sexual stimuli?...
by Determined-Mind
Thu Apr 25, 2024 4:01 pm
Forum: PSSD related research
Topic: My theory for overnight PSSD upon 2nd, or 3rd SSRI
Replies: 1
Views: 231

Re: My theory for overnight PSSD upon 2nd, or 3rd SSRI

Interesting stuff. This same theory of memory and prediction could explain the persistent disorders induced by chronic stress (repeated trauma).

If you have any treatment ideas to regenerate the expression of the original genome...
by Determined-Mind
Sat Apr 20, 2024 10:00 am
Forum: General
Topic: Interested to hear from anyone that improved significantly, after years of pssd
Replies: 4
Views: 597

Re: Interested to hear from anyone that improved significantly, after years of pssd

I'm a woman, I'm 30 and I've had sexual dysfunction since probably at least adolescence (complex trauma = chronic stress during childhood + adolescence). I improved with 150 mg bupropion alone and 300 mg bupropion + 20 mg buspirone). I then experienced a worsening and I suspect a paradoxical reactio...
by Determined-Mind
Sat Apr 20, 2024 9:57 am
Forum: Treatments and experimentation
Topic: My experience with low-dose lithium orotate and its cognitive and sexual improvements
Replies: 0
Views: 218

My experience with low-dose lithium orotate and its cognitive and sexual improvements

I experienced my first sexual improvement with lithium last night with my husband! We were both impressed. The road to recovery is still long, but this mineral gives us great hope. I'm going to use this thread to share with you all my improvements and experiments with lithium over the next few month...
by Determined-Mind
Sat Apr 20, 2024 9:12 am
Forum: General
Topic: About cognitive symptoms..
Replies: 1
Views: 287

Re: About cognitive symptoms..

I have some cognitive problems (such as auto-biographical memory problems) without at the moment knowing any improvement on that after taking a variety of substances. People with cognitive problems can certainly benefit from stimulants (like methylphenidate, modafinil or herbs like a combination of ...
by Determined-Mind
Thu Apr 18, 2024 10:11 am
Forum: Treatments and experimentation
Topic: no improvement yet on lithium
Replies: 8
Views: 452

Re: no improvement yet on lithium

The massage + lithium combination can certainly help. In my opinion, it should be tried every day for people with numbness. Touch is one of the things that can stimulate neuroplasticity, and lithium is known to stimulate neuroplasticity too. That said, I have my doubts as to whether improvement in p...
by Determined-Mind
Wed Apr 17, 2024 10:40 am
Forum: Treatments and experimentation
Topic: no improvement yet on lithium
Replies: 8
Views: 452

Re: no improvement yet on lithium

Just to let you know, from what I've read about the use of lithium for PSSD, it's recommended (by Meso, a neuropharmacologist specializing in PSSD) to take it below 400 mg lithium carbonate (40 mg lithium orotate) because at therapeutic doses for bipolar patients, it's pro-anhedonia and pro-sexual d...
by Determined-Mind
Wed Apr 10, 2024 6:21 am
Forum: Treatments and experimentation
Topic: possible upregulation of receptors with Huperzine A?
Replies: 6
Views: 553

Re: possible upregulation of receptors with Huperzine A?

The only way to know if a substance works for you is to try it.

There have been studies with Huperzine A for Alzheimer's disease.

From memory, the therapeutic dosage was 400 mcg.
by Determined-Mind
Tue Apr 02, 2024 10:11 am
Forum: General
Topic: PSSD in 2024 and beyond: Meso's thoughts
Replies: 7
Views: 1286

Re: PSSD in 2024 and beyond: Meso's thoughts

Thank you for the good news and I'm sorry to hear that you have multiple sclerosis. In 2021 you created the thread " Symptoms and their specific treatments ", I'd be curious to read you about it today, especially about the lack of pleasure sensations (physical anhedonia) on the genital are...
by Determined-Mind
Mon Apr 01, 2024 12:17 pm
Forum: Treatments and experimentation
Topic: Lithium orotate + DHEA
Replies: 9
Views: 592

Re: Lithium orotate + DHEA

Actually, on rereading, if she hadn't stopped SSRIs, it wasn't PSSD but a medication-related side effect.

PSSD is reported 6 months after stopping the medication and is persistent sexual dysfunction - without any drugs.