You're welcome here! The brain is amazing... The scientific literature points to sertraline as a possible treatment for PGAD https://pubmed.ncbi.nlm.nih.gov/35575043/ after being induced by lamotrigine. Each drug may have the opposite effect in different people. Perhaps some interesting information ...

personally i know a woman that was 30 years with genital numbness because she couldn't stop SSRI's. Two years ago she regain sensitivity. I asked her if by any chance she took lithium and she said yes, 3 or 4 years ago she was precribed lithium. Wow What a story of hope! 30 years with genital numbn...

Thanks, that's interesting! It gives us hope! That said, PIEZO2 might not be involved in the pleasure of sensations : In clinical evaluations and surveys, three men and two women with PIEZO2-deficiency syndrome reported severe hyposensitivity in genital sensation. Despite their marked mechanosensory...

Lithium is lithium, whether in carbonate or orotate form. This recent study suggests that lithium orotate may be 10 times more potent than lithium carbonate (2023) : https://pubmed.ncbi.nlm.nih.gov/37356352/ In other words, 10 mg of lithium orotate could be equivalent to 100 mg of lithium carbonate....

What substances have helped you recover?

Thank you for this very interesting article. I'm going to print it out and give it to my doctor next time I see him. I'm also thinking of attaching this article, which I found enlightening: https://www.ourbodiesourselves.org/blog/when-antidepressants-leave-lasting-damage-living-with-post-ssri-snri-s...

Other positive testimonials with Lamictal for PSSD: https://coda.io/d/Treatment-options-for-sexual-dysfunctions-and-PSSD_dBTFx_oXX31/Medicine_suPEX#_luaf4 And here on this forum : I wanted to let people know that thanks to my suicidal depression, I had to add a new drug to my 600mg of lithium carbon...

It depends for whom. Some people find lamictal beneficial to their sexual function. For Bipolar Disorder "Post concussion, leading to: explosive outbursts, withdrawal from activities I used to enjoy, addictive behaviors. I wasn't worried about the skin rash; the evidence is clear when slowly ti...

The many testimonials online are very encouraging: https://www.drugs.com/comments/bupropion-dextromethorphan/auvelity-for-major-depressive-disorder.html?search=&sort_reviews=most_recent Some people feel the benefits very quickly, from the very first days. These testimonials are all the more inte...

Auvelity was approved by the FDA in 2022. It is a combination of bupropion SR (105 mg) with dextromethorphan (45 mg). Dextromethorphan is an over-the-counter anti-cough medication (the Robitussin Brand offers a product without any combination of other substances). A June 2022 study indicates that Au...