I haven’t noticed any direct PSSD related change but know that sucralose definitely makes me depressed, so there’s potential the artificial sweeteners could be affecting you.

Thanks for your supportive words. I do relate to your belief that the feelings are still there somewhere, your brain just can’t access them. However after 9 years I don’t hold much hope that I’ll ever be able to. I have not tried any other substances since getting PSSD, just antibiotics a couple of ...

I thought I'd share here my experience with being pregnant with PSSD in case it's of help or interest to anyone, before I have a new addition to occupy me. I've been suffering PSSD for about 9 years now, after taking Cymbalta for 1 year, and am eight months pregnant. As others have reported, there s...

I'm so sorry to hear your experience. I've been with PSSD for around 9 years now, and a couple of years ago, like you, did consult with a surgeon for pudendal nerve surgery. Fortunately my gut reaction was that the risks (e.g. incontinence) were not worth the potential benefits - I knew my other sym...

Just joining in to say that I have often wondered about PSSD being linked to inflammation. I was a high level athlete when I came off cymbalta. Since that point my body really struggled with inflammation, training sessions that I had previously done without issues would leave me feeling so inflamed ...

I realise this thread is old, but yes. Female who was on cymbalta for one year and been suffering PSSD for 8 years now.