Search found 80 matches
- Fri Mar 18, 2022 5:57 pm
- Forum: PSSD related research
- Topic: Final theory of PSSD etiology. Get in here!
- Replies: 85
- Views: 19918
Re: Final theory of PSSD etiology. Get in here!
Any updates or new trials?
- Thu Mar 17, 2022 8:13 pm
- Forum: Treatments and experimentation
- Topic: Cyclothiazide big erection promotor?
- Replies: 0
- Views: 637
Cyclothiazide big erection promotor?
https://en.wikipedia.org/wiki/Cyclothiazide "a positive allosteric modulator of the AMPA " (more glutamate) "eliminating rapid desensitization of the (AMPA) receptor" receptor more sensitive "GABAA receptor negative allosteric modulator" = more non contact erections htt...
- Fri Mar 04, 2022 8:28 pm
- Forum: General
- Topic: 12 YEARS LATER. STILL SAME.
- Replies: 32
- Views: 6884
Re: 12 YEARS LATER. STILL SAME.
Berberine and evodiamine are supposed to upregulate SERT mrna, with SERT downregulation an actually documented effect of serotonin related anti depressants. https://pubmed.ncbi.nlm.nih.gov/21647174/ I personally cant stand that "gut theory" of pssd. Max cringe and so forced. Total distract...
- Thu Mar 03, 2022 3:08 pm
- Forum: Treatments and experimentation
- Topic: My theory - Etiology of PSSD and potential treatment.
- Replies: 40
- Views: 13187
- Wed Feb 23, 2022 1:28 am
- Forum: PSSD related research
- Topic: Final theory of PSSD etiology. Get in here!
- Replies: 85
- Views: 19918
Re: Final theory of PSSD etiology. Get in here!
https://pubmed.ncbi.nlm.nih.gov/8131066/ Myo-inositol reduces serotonin (5-HT2) receptor induced homologous and heterologous desensitization Have you tried lithium, sjw or inositol? If so what did you experience? -Myo-Inositol 2 grams increased erections and libido a bit 30-35%, one day after takin...
- Sun Feb 20, 2022 11:08 pm
- Forum: Treatments and experimentation
- Topic: Currently on Fenclonine
- Replies: 24
- Views: 7271
Re: Currently on Fenclonine
Any update on the results of Fenclonine? Plz dm about a possible source.
- Fri Feb 04, 2022 4:41 pm
- Forum: Treatments and experimentation
- Topic: 29 Year Old Male Low libido and Erectile Dysfunction
- Replies: 4
- Views: 1271
Re: 29 Year Old Male Low libido and Erectile Dysfunction
Have you tried TRT to get your testosterone levels up? its irresponsible to suggest this without mentioning that your nuts shrink on TRT alone, over time. Please try to be less destructive in your advice. You'll want to try a mix of HCG and TRT to keep your natural Testosterone production from cras...
- Fri Jan 21, 2022 6:24 pm
- Forum: PSSD related research
- Topic: An Excellent Explaination of How SSRI's Inhibit Sert
- Replies: 85
- Views: 90243
Re: An Excellent Explaination of How SSRI's Inhibit Sert
We want to try to activate wnt in the brain, particularly in the dorsal raphe, but can't find anything that does yet. I'm going to microdose simovastin when it arrives which will probably be sometime later this month or February. It activates wnt in the hippocampus in mice so it might activate in t...
- Fri Jan 21, 2022 6:21 pm
- Forum: PSSD related research
- Topic: Final theory of PSSD etiology. Get in here!
- Replies: 85
- Views: 19918
Re: Final theory of PSSD etiology. Get in here!
https://pubmed.ncbi.nlm.nih.gov/8131066/
Myo-inositol reduces serotonin (5-HT2) receptor induced homologous and heterologous desensitization
Myo-inositol reduces serotonin (5-HT2) receptor induced homologous and heterologous desensitization
- Tue Jan 18, 2022 10:48 am
- Forum: PSSD related research
- Topic: An Excellent Explaination of How SSRI's Inhibit Sert
- Replies: 85
- Views: 90243
Re: An Excellent Explaination of How SSRI's Inhibit Sert
@Tree This says simvastatin inhibits wnt: https://www.mdpi.com/1420-3049/24/9/1782/htm "Simvastatin was found to attenuate H2O2-induced human umbilical vein endothelial cells (HUVECs) dysfunction and inhibit the Wnt/β-catenin pathway" This says simvastain activates wnt: https://app.dimensi...