Search found 20 matches

by capitalCK
Sat Feb 20, 2021 6:16 pm
Forum: Treatments and experimentation
Topic: PSSD for 3 years, corticosteroids temporarily cured all PSSD symptoms
Replies: 79
Views: 23941

Re: PSSD for 3 years, corticosteroids temporarily cured all PSSD symptoms

Wouldn't Adrenal Cortex or Adrenal Glandular also provide corticosteroids?
by capitalCK
Sat Feb 20, 2021 6:57 am
Forum: PSSD related research
Topic: PSSD Genome Project [Megathread]
Replies: 320
Views: 305151

Re: PSSD Genome Project [Megathread]

Ghost. I came to this site via your blog. Thanks for great work you're doing. I don't have PSSD but rather PAS and PFS. Well, the PFS part is a combination of Finasteride+Minoxodil topical combo. I do have 23andMe and happy to send it. I think the genes responsible for nNOS, eNOS, iNOS are probably ...
by capitalCK
Fri Feb 19, 2021 5:33 pm
Forum: Treatments and experimentation
Topic: Theories/Hypothesis - Epigenetics & Accumulation of Metals
Replies: 9
Views: 2091

Re: Theories/Hypothesis - Epigenetics & Accumulation of Metals

@Meso - I just looked through my suitcase (I carried a whole suitcase of supplements etc with me) and found 1 un-used bottle of compounded 20% Testosterone cream . At first I was prescribed 3 clicks a day but then we switched to injections so I guess a bottle remain un-used. On 3 clicks, I remember ...
by capitalCK
Fri Feb 19, 2021 5:13 pm
Forum: Treatments and experimentation
Topic: Theories/Hypothesis - Epigenetics & Accumulation of Metals
Replies: 9
Views: 2091

Re: Theories/Hypothesis - Epigenetics & Accumulation of Metals

Neuronal Nitric Oxide Synthase (nNOS) https://www.sciencedirect.com/topics/neuroscience/neuronal-nitric-oxide-synthase Maybe the root of many SSRI problems. Yep. I think it is some gene being silenced, the gene responsible for producing various Synthase enzymes Neuronal nOS, endothelial eNOS etc. T...
by capitalCK
Fri Feb 19, 2021 4:51 pm
Forum: Treatments and experimentation
Topic: Theories/Hypothesis - Epigenetics & Accumulation of Metals
Replies: 9
Views: 2091

Re: Theories/Hypothesis - Epigenetics & Accumulation of Metals

When you say TRT - do you mean both Testosterone + HCG or only Testosterone? Here is the thing - Post Accutane: Cialis used to work. But I was diagnosed with Hypothyroid and Low T (probably caused by Post Accutane). I went on Levothyroxine and Testosterone + HCG + Anastrazol for a year and a half. A...
by capitalCK
Fri Feb 19, 2021 3:40 pm
Forum: Treatments and experimentation
Topic: Theories/Hypothesis - Epigenetics & Accumulation of Metals
Replies: 9
Views: 2091

Re: Theories/Hypothesis - Epigenetics & Accumulation of Metals

After developing PSSD, I had a lot of symptoms related to lack of NO. They never improved with time, but were completely reversed with NO supplementation. Your second hypothesis seems plausible. For me, NO supplemention hasn't helped. Taking nitrates in form of Spinach, Arugula, Beets. Or precurors...
by capitalCK
Fri Feb 19, 2021 11:54 am
Forum: Treatments and experimentation
Topic: Theories/Hypothesis - Epigenetics & Accumulation of Metals
Replies: 9
Views: 2091

Theories/Hypothesis - Epigenetics & Accumulation of Metals

My problems started with Accutane but things like Cialis 5mg would return sexual function to normal and I ignored other symptoms. Then few years later, I took Minoxidil + Finasteride topical combo from MinoxidilMax. And then all symptoms became worse and I stopped responding to Cialis etc, no matter...
by capitalCK
Fri Sep 18, 2020 2:57 pm
Forum: Treatments and experimentation
Topic: PAS/PFS/PSSD treatment, critique and correct, Please! (Test Results Attached)
Replies: 12
Views: 4608

Re: PAS/PFS/PSSD treatment, critique and correct, Please! (Test Results Attached)

Sex hormones silences and dopamine receptor silences ( D1 and D2)+ neurotransmitters depletion ( dopamine, norepinephrine, serotonin and histamine). Thanks. Are you being charged by the word? Your message is too short/without enough context so I'm having a hard time what you mean. But thank you for...
by capitalCK
Thu Sep 17, 2020 2:06 am
Forum: Treatments and experimentation
Topic: PAS/PFS/PSSD treatment, critique and correct, Please! (Test Results Attached)
Replies: 12
Views: 4608

Re: PAS/PFS/PSSD treatment, critique and correct, Please! (Test Results Attached)

Avoid any methyl donors. I found out for myself what they are doing with me. But at least I know what caused my problem 3 years ago. Cannabigerol is strong alpha 2 agonist, and downregulate this in long term use, this is bad for society life. Low alpha2 ( high norepinephrine) create very empathetic...